Peroral delivery systems based on superporous hydrogel

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superporus hydrogel - SlideShare

Dec 13,2012 Peroral delivery systems based on superporous hydrogel#0183;DEVELOPMENT OF PERORAL PEPTIDE DELIVERY SYSTEMS Superporous hydrogels and their composites that increase their volume by about 200-fold.Such volume increase allowed the gels to mechanically stick to the intestinal gut wall and deliver the incorporated drug directly to the gut wall.e.g.buserelin,octreotide and insulin 12/4/2012 SUPERPORUS Topical Vaginal Drug Delivery System Based on Superporous Title:Topical Vaginal Drug Delivery System Based on Superporous Hydrogel Hybrids VOLUME 21 ISSUE 11 Author(s):Hitesh Chavda,Gordhan Chavada,Jaimeen Patel,Kiran Rangpadiya and Chhagan Patel Affiliation:Department of Pharmaceutics and Pharmaceutical Technology,Shri Sarvajanik Pharmacy College,Gujarat Technological University,Mehsana,Gujarat 384 001,India.Topical Vaginal Drug Delivery System Based on Superporous Title:Topical Vaginal Drug Delivery System Based on Superporous Hydrogel Hybrids VOLUME 21 ISSUE 11 Author(s):Hitesh Chavda,Gordhan Chavada,Jaimeen Patel,Kiran Rangpadiya and Chhagan Patel Affiliation:Department of Pharmaceutics and Pharmaceutical Technology,Shri Sarvajanik Pharmacy College,Gujarat Technological University,Mehsana,Gujarat 384 001,India.

Superporous polyacrylate/chitosan IPN hydrogels for

Peroral delivery systems based on superporous hydrogel polymers release characteristics for the peptide drugs buserelin,octreotide and insulin.Eur J Pharm Sci.2004;15:4339.ArticleSuperporous hydrogels containing poly(acrylic acid-co Feb 01,2007 Peroral delivery systems based on superporous hydrogel#0183;A.Polnok,J.C.Verhoef,G.Borchard,N.Sarisuta,H.E.JungingerIn vitro evaluation of intestinal absorption of desmopressin using drug-delivery systems based on superorous hydrogels Int J Pharm,269 (2004),pp.303-310Superporous hydrogels - SlideShareJul 17,2017 Peroral delivery systems based on superporous hydrogel#0183;Superporous hydrogels 1.SUPERPOROUS HYDROGELS PRESENTED BY M.SRAVANTHI M.PHARM-I Yr Dept.Of.Pharmaceutics SpSp.2.INTRODUCTION The oral drug delivery system is the most suitable method for administration of drug.About 80% of the orally administered drugs are excreted without absorbed.

Superporous Hydrogels for Drug Delivery Systems

1.131.11.2.Peroral Intestinal Delivery 574 1.131.11.3.SPHs as Diet Aid 574 1.131.11.4.SPHs as Superdisintegrant 574 1.131.11.5.Other Applications 574 1.131.12.Conclusions 575 References 575 Abbreviations aq Aqueous CD Circular dichroism CMC Carboxymethylcellulose CSPHs Conventional superporous hydrogels DDS Drug delivery systemSuperporous Hydrogels for Drug Delivery Systems1.131.11.2.Peroral Intestinal Delivery 574 1.131.11.3.SPHs as Diet Aid 574 1.131.11.4.SPHs as Superdisintegrant 574 1.131.11.5.Other Applications 574 1.131.12.Conclusions 575 References 575 Abbreviations aq Aqueous CD Circular dichroism CMC Carboxymethylcellulose CSPHs Conventional superporous hydrogels DDS Drug delivery systemSome results are removed in response to a notice of local law requirement.For more information,please see here.

Recent developments in superporous hydrogels

Recent developments in superporous hydrogels Hossein Omidian,Kinam Pa rk and Jose G.Rocca Abstract Superporous hydrogels (SPHs) were originally developed as a novel drug delivery system to retain drugs in the gastric medium.These systems should instantly swell inRecent developments in superporous hydrogels - Omidian Superporous hydrogels (SPHs) were originally developed as a novel drug delivery system to retain drugs in the gastric medium.These systems should instantly swell in the stomach and maintain their integrity in the harsh stomach environment,while releasing the pharmaceutical active ingredient.Previous123456NextPeroral delivery systems based on superporous hydrogel Peroral delivery systems based on superporous hydrogel polymers Release characteristics for the peptide drugs buserelin,octreotide and insulin

Preparation and In Vitro Evaluation of a Stomach Specific

drug-delivery system based on superporous hydrogel composite containing sodium carboxymethylcellulose as a composite material is promising for stomach specific delivery of ranitidine hydrochloride..Key words Floating drug-delivery system,kinetic modeling,ranitidine hydrochloride,sodium carboxymethylcellulose,superporous hydrogel compositePreparation and In Vitro Evaluation of a Stomach Specific Dec 01,2009 Peroral delivery systems based on superporous hydrogel#0183;Peroral delivery systems based on superporous hydrogel polymers Release characteristics for the peptide drugs buserelin,octreotide and insulin.Eur J Pharm Sci 2002; 15:433-9.Dorkoosh FA,Verhoef JC,Verheijden JH,Rafiee-Tehrani M,Borchard G,Junginger HE.Preparation and In Vitro Evaluation of a Stomach Specific Dec 01,2009 Peroral delivery systems based on superporous hydrogel#0183;Peroral delivery systems based on superporous hydrogel polymers Release characteristics for the peptide drugs buserelin,octreotide and insulin.Eur J Pharm Sci 2002; 15:433-9.Dorkoosh FA,Verhoef JC,Verheijden JH,Rafiee-Tehrani M,Borchard G,Junginger HE.

Polysaccharide-Based Superporous,Superabsorbent,and

This study is carried out on polysaccharide-based hydrogel extracted from the seeds of Ocimum basilicum L.for its evaluation as a superabsorbent and stimuli responsive biomaterial for sustained release drug delivery system.O.basilicum (Syn Basil) seed hydrogel (BSH) expressed high swelling capacity at pH 6.8 and 7.4 and deionized water.Peroral delivery systems based on superporous hydrogel Jun 01,2002 Peroral delivery systems based on superporous hydrogel#0183;Recently,we have developed novel delivery systems based on superporous hydrogel (SPH) and SPH composite (SPHC),which are able to achieve mechanical fixation of the dosage form at desirable site(s) of absorption in the intestine by controlled rapid swelling (Dorkoosh et al.,2001).Peroral absorption of octreotide using delivery systems The aim of this study was to investigate the enhancement of peroral octreotide absorption using delivery systems based on superporous hydrogel (SPH) and SPH composite (SPHC) polymers.

Peroral absorption of octreotide using delivery systems

The aim of this study was to investigate the enhancement of peroral octreotide absorption using delivery systems based on superporous hydrogel (SPH) and SPH composite (SPHC) polymers.PREPARATION AND CHARACTERIZATION OF SUPERPOROUS HYDROGELSGupta N and Shivkumar H Development of gastror-etentive drug delivery system based on SPH.Tropical Journal of Pharmaceutical Research 2010; 9 257-264.Gupta V and Shivkumar H Preparation and characterization of superporous hydrogels as gastro-retentive drug delivery system for rosiglitazone maleate.PREPARATION AND CHARACTERIZATION OF SUPERPOROUS HYDROGELSGupta N and Shivkumar H Development of gastror-etentive drug delivery system based on SPH.Tropical Journal of Pharmaceutical Research 2010; 9 257-264.Gupta V and Shivkumar H Preparation and characterization of superporous hydrogels as gastro-retentive drug delivery system for rosiglitazone maleate.

Implications of superporous hydrogel composites-based

Implications of superporous hydrogel composites-based gastroretentive drug delivery systems with improved biopharmaceutical performance of fluvastatin The superporous hydrogels of fluvastatin exhibited swelling property in presence of the gastric fluid and retains inside the stomach to provide controlled drug release action.GASTRORETENTIVE SUPERPOROUS HYDROGEL TABLETS OF The solubility and absorption can be improved with an increase in the gastric residence time.Superporous hydrogels are a good alternative for providing gastroretentive drug delivery systems for therapeutic management of peptic ulcer 14.MATERIALS METHODS Dexlansoprazole was obtained as gift sample from MSN Laboratories Pvt Ltd,Hyderabad GASTRORETENTIVE SUPERPOROUS HYDROGEL TABLETS OF The solubility and absorption can be improved with an increase in the gastric residence time.Superporous hydrogels are a good alternative for providing gastroretentive drug delivery systems for therapeutic management of peptic ulcer 14.MATERIALS METHODS Dexlansoprazole was obtained as gift sample from MSN Laboratories Pvt Ltd,Hyderabad

Feasibility study on the retention of superporous hydrogel

Sep 30,2004 Peroral delivery systems based on superporous hydrogel#0183;Superporous hydrogel (SPH) and SPH composite (SPHC)-based drug delivery systems were also developed for the targeted delivery of peptide drugs into the intestinal tract.In the present study,the retention time of SPHC polymer is studied in man using the scintigraphy technique.Drug delivery applications for superporous hydrogelshybrid hydrogels,intestinal drug delivery,peroral protein delivery,superdisintegrant,superporous hybrid hydrogels,superporous hydrogels Expert Opin.Drug Deliv.(2011) 9(1):1-19 30 1.Introduction Development of pharmaceutical dosage forms typically begins when a new chemicalDrug delivery applications for superporous hydrogelshybrid hydrogels,intestinal drug delivery,peroral protein delivery,superdisintegrant,superporous hybrid hydrogels,superporous hydrogels Expert Opin.Drug Deliv.(2011) 9(1):1-19 30 1.Introduction Development of pharmaceutical dosage forms typically begins when a new chemical

Development of a Gastroretentive Drug Delivery System

Degradation kinetics showed that chitosan superporous hydrogels had good water retention capability.Drug release was inversely related to the amount of crosslinking agent and fitted best to the Korsmeyer-Peppas model.Conclusion The studies showed that chitosan-based superporous hydrogels can be used as a gastroretentive drug delivery system Cited by 108Publish Year 2002Author Farid A.Dorkoosh,J.Coos Verhoef,Matheus H.C.Ambagts,Morteza Rafiee-Tehrani,Gerrit Borchard,HPeroral delivery systems based on superporous hydrogel Peroral delivery systems based on superporous hydrogel polymers release characteristics for the peptide drugs buserelin,octreotide and insulin.Dorkoosh FA(1),Coos Verhoef J,Ambagts MH,Rafiee-Tehrani M,Borchard G,Junginger HE.Cited by 108Publish Year 2002Author Farid A.Dorkoosh,J.Coos Verhoef,Matheus H.C.Ambagts,Morteza Rafiee-Tehrani,Gerrit Borchard,HPeroral delivery systems based on superporous hydrogel Peroral delivery systems based on superporous hydrogel polymers release characteristics for the peptide drugs buserelin,octreotide and insulin Author links open overlay panel Farid A.Dorkoosh J.Coos Verhoef Matheus H.C.Ambagts Morteza Rafiee-Tehrani Gerrit Borchard Hans E.Junginger

Cited by 108Publish Year 2002Author Farid A.Dorkoosh,J.Coos Verhoef,Matheus H.C.Ambagts,Morteza Rafiee-Tehrani,Gerrit Borchard,HPeroral delivery systems based on superporous hydrogel

Peroral delivery systems based on superporous hydrogel polymers Release characteristics for the peptide drugs buserelin,octreotide and insulinChitosan superporous hydrogel composite-based floating Chitosan superporous hydrogel composite-based floating drug delivery system A newer formulation approach Hitesh Chavda and Chhaganbhai Patel 1 Department of Pharmaceutics and Pharmaceutical Technology,Shri Sarvajanik Pharmacy College,Hemchandracharya North Gujarat University,Mehsana,Gujarat 384 001,IndiaA Novel Peroral Peptide Drug Delivery System Based on May 05,2004 Peroral delivery systems based on superporous hydrogel#0183;We report here the development and testing of a drug carrier system for the peroral delivery of peptide drugs.The carrier system is based on superporous hydrogel (SPH) and SPH composite (SPHC) polymers.Their fast swelling properties result in opening of tight epithelial junctions,allowing for the paracellular route of transport of macromolecular compounds,and the increase of

A Conceptual Overview on Superporous Hydrogels

Superporous hydrogels were originally developed as a novel drug delivery system to retain drugs in the gastric medium for those peroral intestinal peptide and protein absorption.This review discusses the formulation,techniques for synthesizing superporous Acrylamide-based Superporous hydrogels12345NextPeroral delivery systems based on superporous hydrogel Peroral delivery systems based on superporous hydrogel polymers Release characteristics for the peptide drugs buserelin,octreotide and insulin(PDF) Superporous polyacrylate/chitosan IPN hydrogels for Peroral delivery systems based on.superporous hydrogel polymers release characteristics for the. (HEMA),-based superporous hydrogels (SPHs) in interpenetrating network (IPN)/semi-IPN form

(PDF) Superporous hydrogel A promising tool for

Conclusion It is concluded that the proposed bioadhesive,mechanically stable as well as floating drug-delivery system based on superporous hydrogel composite containing Carbopol 934P as a (PDF) Oral insulin delivery systems using chitosan-based Novel peroral peptide drug delivery systems based on superporous hydrogel (SPH) and SPH composite (SPHC) have recently been developed in our laboratory.(PDF) Oral insulin delivery systems using chitosan-based Novel peroral peptide drug delivery systems based on superporous hydrogel (SPH) and SPH composite (SPHC) have recently been developed in our laboratory.

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